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V.F. Fokin, N.V. Ponomareva, M.V. Krotenkova, R.N. Konovalov, M.M. Tanashyan, O.V. Lagoda
Research Center of Neurology of Russian academy of medical science, Moscow, Russian Federation
Two Patterns f Ct-Brain Perfusion And Dc-Potentials f The Brain Evoked Cognitive Task in Discirculatory Encephalopathy Patients
In patients with discirculatory encephalopathy the influence of verbal fluency test on the characteristics of cerebral perfusion, DC-potentials of the brain, as well as on blood pressure and heart rate was investigated. Two patterns of responses to the verbal fluency test were observed. The first one is the process of generalized activation, manifested by the reduction of the TTP (time to peak) parameters of brain perfusion, the rise of the DC-potentials in all areas of brain and the modulation of blood pressure and heart rate. The second process, directly connected with cognitive processing, was manifested by the shifts of local characteristics of brain perfusion and DC-potentials in the frontal, temporal and central cortex, especially in the left hemisphere. Correlations were found between the characteristics of cerebral perfusion and DC-potentials on the one hand and the number of words during the verbal fluency test performance on the other hand.
Keywords: CT-brain perfusion, DC-potentials of the brain, verbal fluency, discirculatory encephalopathy.
(Vestnik Rossiiskoi akademii meditsinskikh nauk Annals of the Russian Academy of Medical Sciences. 2012. 10:3843).
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